[Advayavada Study Plan – week 1 of 13] Anicca (Pali) or anitya (Sanskrit) means impermanent, changeable, unstable, transitory, and it is the first of the three (in Advayavada Buddhism, four) signs or marks or basic facts of being. The Buddhist aniccata or anityata doctrine teaches that impermanence or changeability is the most fundamental property of everything existing; it lies at the very heart of the interdependent origination (madhyamaka-pratityasamutpada) and emptiness (shunyata) of all things, and evolution, progress and liberation would not be possible without it – karma is, in Advayavada Buddhism, this incessant universal process of interdependent origination of all things as it is undergone and experienced by sentient beings, our individual share of it being the everchanging knotlet of biopsychosocial (bps) events in which we are personally embedded.